Doctors often cannot explain why one person develops cancer and another does not. But research shows that certain risk factors increase the chance that a person will develop cancer.
On August 31st 2013 friends and members of SAOF met at Hillyfields Medial Centre, London for the SAOF SUMMER LONDON meeting of the foundation. Issues discussed include an update on activities of SAOF and a scientific section on BREAST CANCER RISK Factors,
Breast Cancer is the commonest cause of cancer death in women worldwide. Rates vary about five-fold around the world, but they are increasing in regions that until recently had low rates of the disease.
Many of the established risk factors are linked to Age factor, Genetics, Obesity, Menstruating young, Giving birth after 35, Radiation, Female factor, Family history, Consuming alcohol, Hormone therapy. Risk is increased by early menarche, late menopause, and obesity in postmenopausal women, and prospective studies have shown that high concentrations of endogenous oestradiol are associated with an increase in risk. Childbearing reduces risk, with greater protection for early first birth and a larger number of births; breastfeeding probably has a protective effect. Both oral contraceptives and hormonal therapy for menopause cause a small increase in breast-cancer risk, which appears to diminish once use stops. Alcohol increases risk, whereas physical activity is probably protective. Mutations in certain genes greatly increase breastcancer risk, but these account for a minority of cases.